Methotrexate: clinical pharmacology, current status and therapeutic guidelines

Cancer Treat Rev. 1977 Jun;4(2):87-101. doi: 10.1016/s0305-7372(77)80007-8.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Antineoplastic Agents / therapeutic use
  • Drug Interactions
  • Drug Therapy, Combination
  • Folic Acid Antagonists
  • Half-Life
  • Humans
  • Leucovorin / pharmacology
  • Leukoencephalopathy, Progressive Multifocal / chemically induced
  • Liver / drug effects
  • Methotrexate / administration & dosage
  • Methotrexate / adverse effects
  • Methotrexate / metabolism
  • Methotrexate / pharmacology*
  • Methotrexate / therapeutic use
  • Neoplasms / drug therapy*
  • Neoplasms / metabolism

Substances

  • Antineoplastic Agents
  • Folic Acid Antagonists
  • Leucovorin
  • Methotrexate