[Fatal invasive pulmonary aspergillosis in a patient with multiple non-classic risk factors]

Rev Med Inst Mex Seguro Soc. 2019 Dec 30;57(6):400-405.
[Article in Spanish]

Abstract

Background: Pulmonary aspergillosis is a severe invasive infection that mainly affects immunocompromised patients, causing a great mortality.

Clinical case: We present a male patient with chronic ethilism, diabetes mellitus, and work exposure of inhalated harmful chemicals, who had a fatal outcome, that even when not presenting typical risk factors, developed a clinical presentation compatible, and mycological evaluation that support the diagnosis of a probably invasive pulmonary aspergillosis.

Conclusion: The effect of the combination of the described non-typical situations as predisposing factors for pulmonary aspergillosis requires further research, given that they are non-typical factors.

Introducción: la aspergilosis pulmonar es una infección invasiva severa que afecta principalmente a pacientes inmunocomprometidos y representa una causa importante de mortalidad.

Caso clínico: presentamos un paciente con antecedentes de etilismo crónico, diabetes mellitus y exposición laboral recurrente a sustancias químicas nocivas inhaladas, quien tuvo un desenlace fatal, y que, incluso al no presentar factores de riesgo típicos, desarrolló una presentación clínica compatible y tuvo estudios micológicos que apoyan el diagnóstico de una probable aspergilosis invasiva.

Conclusión: el efecto de la combinación de tales situaciones no típicas como factores predisponentes de aspergilosis pulmonar amerita mayor investigación, dado que se trata de factores de riesgo no típicos.

Keywords: Coinfection; Lung Diseases; Pulmonary Aspergillosis.

Publication types

  • Case Reports

MeSH terms

  • Alcoholism / complications
  • Aspergillus fumigatus / isolation & purification
  • Candida albicans / isolation & purification
  • Candidiasis, Invasive / diagnosis*
  • Candidiasis, Invasive / microbiology
  • Coinfection / diagnosis*
  • Coinfection / microbiology
  • Diabetes Mellitus, Type 2 / complications
  • Environmental Pollutants / toxicity
  • Fatal Outcome
  • Humans
  • Immunocompromised Host*
  • Invasive Pulmonary Aspergillosis / diagnosis*
  • Invasive Pulmonary Aspergillosis / microbiology
  • Male
  • Middle Aged
  • Occupational Exposure / adverse effects
  • Pseudomonas Infections / diagnosis*
  • Pseudomonas Infections / microbiology
  • Pseudomonas aeruginosa / isolation & purification
  • Risk Factors

Substances

  • Environmental Pollutants