Endometriosis and Reproduction: What We Have Learned

Yale J Biol Med. 2020 Sep 30;93(4):571-577. eCollection 2020 Sep.

Abstract

Endometriosis, despite only affecting 10-15% of women of fertile age, is still an enigmatic disease. Recent developments in assisted reproductive technology have contributed to a better understanding of where and how endometriosis could compromise fertility. In this mini-review we will show how the main point of damage in endometriosis is quantitative impairment of the ovaries, if the "less is more" mantra should be applied when considering ovarian surgery, and when fertility preservation prior to ovarian surgery could be considered. Endometrial receptivity, however, does not seem to be affected.

Keywords: assisted reproductive techonology; endometriosis; fertility preservation; ovarian reserve.

Publication types

  • Review

MeSH terms

  • Endometriosis*
  • Female
  • Fertility
  • Fertility Preservation*
  • Humans
  • Reproduction
  • Reproductive Techniques, Assisted