Yttrium-90 selective internal radiotherapy as bridge to curative hepatectomy for recurrent malignant solid pseudopapillary neoplasm of pancreas: case report and review of literature

Adam R Dyas; David Thor Johnson; Erin Rubin; Richard D Schulick; Piyush Kumar Sharma

doi:10.1093/jscr/rjaa325

Yttrium-90 selective internal radiotherapy as bridge to curative hepatectomy for recurrent malignant solid pseudopapillary neoplasm of pancreas: case report and review of literature

J Surg Case Rep. 2020 Sep 25;2020(9):rjaa325. doi: 10.1093/jscr/rjaa325. eCollection 2020 Sep.

Authors

Adam R Dyas¹, David Thor Johnson², Erin Rubin³, Richard D Schulick¹, Piyush Kumar Sharma¹

Affiliations

¹ Department of Surgery, University of Colorado School of Medicine, Aurora, CO, USA.
² Department of Radiology, University of Colorado School of Medicine, Aurora, CO, USA.
³ Department of Pathology, University of Colorado School of Medicine, Aurora, CO, USA.

Abstract

Recurrent malignant solid pseudopapillary neoplasms of the pancreas (SPNP) are rare tumors with unpredictable clinical and histopathological features. There is a lack of consensus regarding utilization of adjuvant modalities in conjunction with or in lieu of curative metastatectomy. We present a remarkable case where Yttrium-90 selective internal radiation therapy (Y-90 SIRT) was successfully utilized to elucidate underlying tumor biology and aid resection of a large multifocal recurrent metastatic SPNP in the right hemi-liver of a 59-year-old female. Thus, in cases where curative metastatectomy remains the treatment goal in management of recurrent and/or metastatic SPNPs, Y-90 SIRT is a safe and effective adjunct treatment to facilitate curative resection.

Publication types

Case Reports