Identification and Clinical Application of Immunological Receptors Targeting Mutated Antigens Expressed by Solid Tumors

Cancers (Basel). 2020 Sep 30;12(10):2818. doi: 10.3390/cancers12102818.


In the recent years, immunotherapy has achieved impressive results utilizing different approaches, from (chimeric antigen receptor) CAR-T cells directed against CD19 for the treatment of leukemia and lymphomas to the Nobel prize-winning strategy of check-point inhibition for the treatment of several solid tumors [...].

Keywords: CAR; TCR; clinical trials; mutated antigens; solid tumors.

Publication types

  • Editorial