Prolonged incubation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a patient on rituximab therapy

Infect Control Hosp Epidemiol. 2021 Oct;42(10):1286-1288. doi: 10.1017/ice.2020.1239. Epub 2020 Oct 7.

Abstract

The incubation period of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is rarely >14 days. We report a patient with hypogammaglobulinemia who developed coronavirus disease 2019 (COVID-19) with a confirmed incubation period of at least 21 days. These findings raise concern for a prolonged presymptomatic transmission phase, necessitating a longer quarantine duration in this patient population.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • COVID-19*
  • Humans
  • Quarantine
  • Rituximab / therapeutic use
  • SARS-CoV-2*
  • Time Factors

Substances

  • Rituximab