Comparison of Inflammatory Markers between Adult and Pediatric Brucellosis Patients

Rev Soc Bras Med Trop. 2020 Oct 5:53:e20190356. doi: 10.1590/0037-8682-0356-2019. eCollection 2020.

Abstract

Introduction: This study aimed to evaluate and compare with healthy control subjects the levels of indirect inflammatory markers such as mean platelet volume (MPV), platelet to lymphocyte ratio (PLR), and neutrophil to lymphocyte ratio (NLR) in adults and children with brucellosis.

Methods: White blood cell, neutrophil, lymphocyte, and platelet counts, and C-reactive protein (CRP) levels were retrospectively recorded for all participants.

Results: NLR and neutrophil counts were significantly higher in adult patients compared to those in pediatric patients.

Conclusions: Indirect inflammatory markers such as NLR, PLR, MPV, red distribution width, and CRP levels may be helpful for follow-up of brucellosis.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Biomarkers
  • Brucellosis*
  • Child
  • Humans
  • Mean Platelet Volume*
  • Middle Aged
  • Platelet Count
  • Retrospective Studies
  • Young Adult

Substances

  • Biomarkers