Epithelioid hemangioendothelioma and related lesions

Semin Diagn Pathol. 1986 Nov;3(4):259-87.


Epithelioid hemangioendothelioma (EH) is the prototype of a group of vascular tumors characterized by an epithelioid or histiocytoid endothelial cell. This family also includes the epithelioid hemangioma (angiolymphoid hyperplasia with eosinophilia) and epithelioid forms of angiosarcoma. This review discusses the principal clinical, pathologic, and biologic differences among these three lesions. In particular the various manifestations of EH of soft tissue, bone, lung (previously called intravascular bronchioloalveolar tumor), and liver are discussed. Long-term follow-up data of EH of soft tissue and lung are provided.

Publication types

  • Comparative Study
  • Review

MeSH terms

  • Bone Neoplasms / pathology
  • Hemangioendothelioma / pathology*
  • Humans
  • Liver Neoplasms / pathology
  • Lung Neoplasms / pathology*
  • Soft Tissue Neoplasms / pathology