Thrombotic complications of COVID-19

Am J Emerg Med. 2020 Oct 1;S0735-6757(20)30860-3. doi: 10.1016/j.ajem.2020.09.065. Online ahead of print.

Abstract

Introduction: The novel coronavirus disease of 2019 (COVID-19) is associated with significant morbidity and mortality. The impact of thrombotic complications has been increasingly recognized as an important component of this disease.

Objective: This narrative review summarizes the thrombotic complications associated with COVID-19 with an emphasis on information for Emergency Medicine clinicians.

Discussion: Thrombotic complications from COVID-19 are believed to be due to a hyperinflammatory response caused by the virus. Several complications have been described in the literature. These include acute limb ischemia, abdominal and thoracic aortic thrombosis, mesenteric ischemia, myocardial infarction, venous thromboembolism, acute cerebrovascular accident, and disseminated intravascular coagulation.

Conclusion: It is important for Emergency Medicine clinicians to be aware of the thrombotic complications of COVID-19. Knowledge of these components are essential to rapidly recognize and treat to reduce morbidity and mortality in these patients.

Keywords: COVID-19; Coronavirus; Emergency medicine; SARS-CoV-2; Thrombosis; Thrombotic.

Publication types

  • Review