Topical niacinamide enhances hydrophobicity and resilience of corneocyte envelopes on different facial locations

Int J Cosmet Sci. 2020 Dec;42(6):632-636. doi: 10.1111/ics.12666.

Abstract

Age-related differences in maturation parameters of corneocyte envelopes (size, hydrophobicity and rigidity) were examined at several facial test sites in young and old female Caucasians. In addition, the effect of topically applied niacinamide on these parameters was evaluated in a 4-week placebo-controlled study.

Publication types

  • Letter
  • Randomized Controlled Trial

MeSH terms

  • Administration, Topical
  • Adult
  • Face*
  • Female
  • Humans
  • Hydrophobic and Hydrophilic Interactions
  • Middle Aged
  • Niacinamide / administration & dosage
  • Niacinamide / pharmacology*
  • Placebos
  • Skin / cytology
  • Skin / drug effects*

Substances

  • Placebos
  • Niacinamide