The incidence of vascular cognitive impairment (VCI) has been increasing for years and has become a major disabling factor in middle-aged and elderly populations. The pathogenesis of VCI is unclear, and there are no standard diagnostic criteria. Resting-state functional magnetic resonance imaging (rs-fMRI) can be used to detect spontaneous brain functional activity in a resting state, which facilitates in-depth investigation of the pathogenesis of VCI and provides an objective reference for early diagnosis, differential diagnosis, and prognostic evaluation. This article mainly reviews the principle and analysis of rs-fMRI data, as well as the progress of its application for VCI diagnosis.
Keywords: amplitude of low frequency fluctuation; default mode network; functional network; regional homogeneity; resting-state functional magnetic resonance imaging; traumatic brain injury; vascular cognitive impairment.
Copyright © 2020 Wang, Liu, Tao, Gong, Zheng, Yang, Yang and Zhang.