The association of health behaviors with quality of life in lymphoma survivors

Leuk Lymphoma. 2021 Feb;62(2):271-280. doi: 10.1080/10428194.2020.1830389. Epub 2020 Oct 13.


The impact of change in health behaviors (physical activity [PA], alcohol and smoking) on quality of life (QOL) in lymphoma survivors is not well understood. We evaluated the associations of health behaviors with QOL domains at diagnosis and at 3-year follow-up (FU3) in 2805 lymphoma survivors. We report clinically significant QOL score differences, defined as scores that exceeded a minimally important difference threshold and were statistically significant. Current smoking was associated with lower QOL at baseline (p < 0.01) and at FU3 (p < 0.01). Meeting the American Cancer Society PA guidelines was associated with better functional wellbeing and overall QOL at FU3 (p < 0.01). An increase in PA from baseline to FU3 was associated with improvement in physical, functional wellbeing and overall QOL at FU3 compared to baseline (p < 0.01). Thus, QOL in lymphoma survivors is associated with their health behaviors and active interventions to promote positive lifestyle changes in lymphoma survivors are needed.

Keywords: Lymphoma and Hodgkin disease; lymphoid leukemia; prognostication.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Exercise
  • Health Behavior
  • Humans
  • Lymphoma* / epidemiology
  • Lymphoma* / therapy
  • Quality of Life*
  • Surveys and Questionnaires
  • Survivors