Biosynthesis and activity of DNA polymerase throughout the mitotic cycle of Physarum polycephalum

FEBS Lett. 1987 Aug 31;221(1):48-54. doi: 10.1016/0014-5793(87)80350-2.


Measurements of DNA polymerase protein levels and polymerase activity through the naturally synchronous mitotic cycle of Physarum polycephalum show that active DNA polymerase-alpha is synthesized throughout the G2 phase, in step with the profile of general protein biosynthesis. Three main components of P. poly-cephalum DNA polymerase of 200, 112 and 70 kDa were found to be immunologically related.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • DNA Polymerase II / biosynthesis*
  • Electrophoresis, Polyacrylamide Gel
  • Immunoassay
  • Interphase
  • Mitosis
  • Molecular Weight
  • Peptide Hydrolases / metabolism
  • Physarum / enzymology*
  • Radioimmunoassay


  • DNA Polymerase II
  • Peptide Hydrolases