HLA-DRB1*11 is a strong risk factor for acquired thrombotic thrombocytopenic purpura in children

Haematologica. 2020 Oct 1;105(10):e531. doi: 10.3324/haematol.2019.241968.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • ADAMTS13 Protein / genetics
  • Child
  • HLA-DQ beta-Chains
  • HLA-DRB1 Chains / genetics
  • Humans
  • Purpura, Thrombotic Thrombocytopenic* / epidemiology
  • Purpura, Thrombotic Thrombocytopenic* / genetics
  • Risk Factors

Substances

  • HLA-DQ beta-Chains
  • HLA-DRB1 Chains
  • ADAMTS13 Protein

Grant support

Funding. this study was partially supported by the National Plan for Rare Diseases of the French Ministry of Health (qualification of the French Reference Centre for Thrombotic Micro-Angiopathies) and the Programme Hospitalier Recherche Clinique AOM 05012 (DRCD Assistance Publique – Hôpitaux de Paris) and a grant from CSLBehring (AP-HP-2017-47-26).