Disseminated intraosseous Kaposi's sarcoma: A rare manifestation of HIV/AIDS

J Med Imaging Radiat Oncol. 2021 Feb;65(1):86-88. doi: 10.1111/1754-9485.13112. Epub 2020 Oct 14.

Abstract

Kaposi Sarcoma (KS), a mucocutaneous cancer that most frequently occurs in the context of Acquired Immunodeficiency Syndrome (AIDS) secondary to Human Immunodeficiency Virus (HIV), is a relatively benign condition, acting more as a marker of immunodeficiency than directly causing harm itself. However, it has been known to spread both locally and in a metastatic fashion, with reports of KS affecting almost all organ systems. One of the most rarely reported areas of involvement is the musculoskeletal system, with secondary osseous spread representing an even smaller subset of these. We report a case of biopsy proven disseminated intraosseous KS involving the entire imaged skeleton that occurred with HIV/AIDS, despite maximal treatment and normal imaging 8 months prior.

Keywords: Kaposi’s sarcoma; acquired immunodeficiency syndrome; computed tomography; human immunodeficiency virus.

Publication types

  • Case Reports

MeSH terms

  • Acquired Immunodeficiency Syndrome / complications
  • Acquired Immunodeficiency Syndrome / diagnostic imaging
  • HIV Infections* / complications
  • HIV Infections* / diagnostic imaging
  • Humans
  • Sarcoma, Kaposi* / diagnostic imaging
  • Sarcoma, Kaposi* / etiology