Solitary rectal ulcer syndrome

Curr Opin Gastroenterol. 2021 Jan;37(1):59-65. doi: 10.1097/MOG.0000000000000689.


Purpose of review: Solitary rectal ulcer syndrome (SRUS) is a rare disease which can puzzle the gastroenterologist. A review of the syndrome and new treatment options are discussed.

Recent findings: Its association with dyssynergia in general supports an important role for pelvic floor biofeedback, which can be successful in patients with SRUS. No other novel.

Summary: Awareness of this benign syndrome is important; endoscopic diagnosis and histological confirmation opens the way to a guided lifestyle therapy with regulation of defecation and pelvic floor biofeedback. A reluctance to proceed to surgery seems warranted. VIDEO ABSTRACT.

Publication types

  • Review
  • Video-Audio Media

MeSH terms

  • Biofeedback, Psychology
  • Colonic Diseases*
  • Humans
  • Rectal Diseases* / diagnosis
  • Rectal Diseases* / therapy
  • Syndrome
  • Ulcer / diagnosis
  • Ulcer / therapy