Olfactory gyrus intracerebral hemorrhage in a patient with COVID-19 infection

J Clin Neurosci. 2020 Sep:79:275-276. doi: 10.1016/j.jocn.2020.07.033. Epub 2020 Jul 23.

Abstract

Since the outbreak with novel corona virus in December 2019, a myriad of different neurological manifestations in patients with COVID-19 infection have been reported. We present a case of non-traumatic intracranial hemorrhage in the olfactory gyrus in a patient who tested positive for SARS-COV-2. The area of hemorrhage is not a common location for spontaneous hemorrhage. Given that loss of smell is considered a relatively common symptom of this pandemic, it is an intriguing association of COVID-19 and olfactory gyrus ICH for neurotropism of SARS-CoV2 for olfactory bulb and glia cells through nasal mucosa. Future studies will need to elucidate the exact mechanism of anosmia from COVID-19 and potential mechanisms leading to ICH.

Keywords: COVID-19; Intracerebral hemorrhage; Olfactory gyrus; SARS-CoV-2 infection.

Publication types

  • Case Reports

MeSH terms

  • Betacoronavirus*
  • COVID-19
  • Cerebral Hemorrhage / diagnostic imaging
  • Cerebral Hemorrhage / etiology*
  • Coronavirus Infections / complications*
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Olfaction Disorders / etiology
  • Pandemics
  • Parietal Lobe / diagnostic imaging*
  • Pneumonia, Viral / complications*
  • SARS-CoV-2
  • Smell