Human chorionic gonadotropin treatment of nonorganic erectile failure and lack of sexual desire: a double-blind study

Urology. 1987 Sep;30(3):216-9. doi: 10.1016/0090-4295(87)90237-8.


Forty-five cases of nonorganic failure (n = 39) or lack of sexual desire (LSD, n = 6) were treated for one month, either with human chorionic gonadotropins (HCG, 5,000 IU I.M. twice per week) or with placebo using a double-blind method. HCG gave better results than placebo (47% vs 12%, p less than 0.05) and improved a higher number of sexual parameters (6/7) than placebo (2/7). HCG effect on sexual behavior did not correlate with the increase in plasma testosterone level: it seems HCG is a useful option in sexologic treatment of erectile failure and LSD.

Publication types

  • Clinical Trial
  • Comparative Study
  • Controlled Clinical Trial

MeSH terms

  • Adult
  • Chorionic Gonadotropin / therapeutic use*
  • Clinical Trials as Topic
  • Double-Blind Method
  • Erectile Dysfunction / drug therapy*
  • Humans
  • Libido*
  • Male
  • Middle Aged
  • Sexual Behavior / drug effects
  • Sexual Dysfunctions, Psychological / drug therapy*
  • Testosterone / blood
  • Testosterone / therapeutic use


  • Chorionic Gonadotropin
  • Testosterone