Chronic non-cancer pain and its association with healthcare use and costs among individuals with obstructive sleep apnea

Pain Manag. 2020 Nov;10(6):377-386. doi: 10.2217/pmt-2020-0012. Epub 2020 Oct 19.

Abstract

Aim: To evaluate the impact of chronic non-cancer pain (CNCP) on healthcare use and costs among individuals diagnosed with obstructive sleep apnea (OSA). Materials & methods: Using the IQVIA PharMetrics® Plus database, we identified individuals (18-64 years old) during 2007-2014, divided into two groups: OSA + CNCP versus OSA-only. Generalized linear models were used to analyze binary and count outcomes. Results: Relative to OSA-only controls, OSA + CNCP cases had increased odds for inpatient and emergency department visits and higher rates for physician office visits, non-physician outpatient visits, and prescription drug fills. Relative to controls, direct healthcare costs for cases were higher, primarily driven by inpatient and non-physician outpatient visit costs. Conclusion: Relative to OSA-only controls, OSA + CNCP cases displayed increased healthcare use and costs across all points of service.

Keywords: chronic non-cancer pain; commercially insured adults; direct medical costs; healthcare use; obstructive sleep apnea.

MeSH terms

  • Adolescent
  • Adult
  • Analgesics, Opioid
  • Chronic Pain* / therapy
  • Delivery of Health Care
  • Humans
  • Middle Aged
  • Retrospective Studies
  • Sleep Apnea, Obstructive* / complications
  • Sleep Apnea, Obstructive* / therapy
  • Young Adult

Substances

  • Analgesics, Opioid