Houston Myopia Control Study: a randomized clinical trial. Part II. Final report by the patient care team

Am J Optom Physiol Opt. 1987 Jul;64(7):482-98.


In a randomized clinical trial designed to test the efficacy of bifocal lenses for the control of juvenile myopia, each of 207 children between the ages of 6 and 15 years wore single vision lenses, +1.00 D add bifocals, or +2.00 D add bifocals for a period of 3 years. For the 124 subjects who completed the study, the mean changes in refraction were found to be -0.34 D per year for subjects wearing single vision lenses, -0.36 D per year for those wearing +1.00 D add bifocals, and -0.34 D per year for those wearing +2.00 D add bifocals. These differences were not statistically significant. When subjects in all three treatment groups were combined, it was found that the rate of progression tended to be the most rapid for subjects who entered the study at an early age with a large amount of myopia, and tended to be the least rapid for subjects who entered the study at a later age with a small amount of myopia. It was also found that subjects having with-the-rule astigmatism progressed more slowly than those having no astigmatism or against-the-rule astigmatism.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Adolescent
  • Age Factors
  • Astigmatism / physiopathology
  • Child
  • Clinical Trials as Topic
  • Eyeglasses*
  • Female
  • Humans
  • Male
  • Myopia / physiopathology
  • Myopia / therapy*
  • Patient Care Team*
  • Random Allocation
  • Refraction, Ocular
  • Sex Factors
  • Statistics as Topic
  • Strabismus / physiopathology