Toxoplasmosis in pregnancy

Eur J Obstet Gynecol Reprod Biol. 2020 Dec:255:44-50. doi: 10.1016/j.ejogrb.2020.10.003. Epub 2020 Oct 8.


Toxoplasmosis is one of the common chronic infections caused by the parasite Toxoplasma gondii. Even though its infection in healthy non-pregnant women is self-limited and largely asymptomatic, the main concern is the risk to the fetus by vertical transmission in pregnancy. Congenital toxoplasmosis can result in permanent neurological damage and even serious morbidity such as blindness. Screening programs are implemented in various countries depending on the prevalence and virulence of the parasite in the respective regions. Upon diagnosis of infection, appropriate antibiotic therapy should be initiated as it has been proven to reduce the risk of fetal transmission. Primary prevention remains the key intervention to avoid the infection and hence patient education is an important aspect of the management.

Keywords: Congenital toxoplasmosis; Mother-to-child transmission; Toxoplasmosis.

MeSH terms

  • Female
  • Humans
  • Infectious Disease Transmission, Vertical / prevention & control
  • Pregnancy
  • Pregnancy Complications, Parasitic* / diagnosis
  • Pregnancy Complications, Parasitic* / drug therapy
  • Pregnancy Complications, Parasitic* / epidemiology
  • Toxoplasma*
  • Toxoplasmosis* / diagnosis
  • Toxoplasmosis* / epidemiology
  • Toxoplasmosis, Congenital* / diagnosis
  • Toxoplasmosis, Congenital* / drug therapy
  • Toxoplasmosis, Congenital* / epidemiology