The adoptive transfer of pregnancy-induced unresponsiveness to male skin grafts with thymus-dependent cells

J Exp Med. 1977 Sep 1;146(3):899-904. doi: 10.1084/jem.146.3.899.

Abstract

A majority of C57BL/10Sn females pregnant six or more times by syngeneic males do not reject male skin grafts. The pregnancy induced tolerance of male skin grafts was transferred adoptively to virgin recipients by thymus-dependent cells from multiparous tolerant donors.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • B-Lymphocytes / immunology
  • Bone Marrow / immunology
  • Bone Marrow Cells
  • Female
  • Histocompatibility Antigens*
  • Immune Tolerance*
  • Immunization, Passive*
  • Male
  • Mice
  • Mice, Inbred C57BL
  • Pregnancy
  • Pregnancy, Animal*
  • Skin Transplantation*
  • Spleen / cytology
  • T-Lymphocytes / immunology*
  • Transplantation, Homologous

Substances

  • Histocompatibility Antigens