Thyroidectomy

Book
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan.
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Excerpt

Thyroidectomy is a surgical procedure involving the resection of the thyroid gland that can be classified into 2 main types: total thyroidectomy, which refers to the complete removal of the thyroid gland, and partial thyroidectomy, which includes procedures such as thyroid lobectomy. Thyroidectomy is indicated for a variety of conditions, including benign disorders such as multinodular goiter, toxic adenomas, and thyroiditis, as well as malignant conditions, including differentiated thyroid carcinoma and anaplastic thyroid carcinoma.

Before undergoing thyroidectomy, patients must have their thyroid function evaluated to assess for hyperthyroidism or hypothyroidism, which could influence perioperative management. Typically, a thyroid ultrasound serves as the initial imaging modality to evaluate the thyroid gland, allowing for the identification of structural abnormalities. If suspicious nodules or lesions are detected, targeted fine-needle aspiration biopsies may be performed to determine these lesions' cytological characteristics and potential malignancy. The decision regarding whether to perform a thyroid lobectomy or total thyroidectomy is contingent upon various factors, including the size, location, and histopathological features of the thyroid pathology.

Surgical complications associated with thyroidectomy can include significant bleeding, which may necessitate reoperation, as well as recurrent laryngeal nerve injury, which can lead to vocal cord paralysis and resultant hoarseness. Additionally, accidental injury to the parathyroid glands can result in postoperative hypoparathyroidism, characterized by hypocalcemia and its associated symptoms. Postoperatively, it is essential to evaluate thyroid function, as many patients may require thyroid hormone replacement therapy to maintain euthyroid status following total thyroidectomy or substantial lobectomy. This comprehensive approach to managing thyroidectomy cases is critical for optimizing surgical outcomes and ensuring long-term health and well-being.

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