Coffee consumption and cancer risk in African Americans from the Southern Community Cohort Study

Sci Rep. 2020 Oct 21;10(1):17907. doi: 10.1038/s41598-020-72993-6.

Abstract

Coffee consumption has been associated with the risk of cancer at several anatomical sites, but the findings, mostly from studies of non-Hispanic whites and Asians, are inconsistent. The association between coffee consumption and the incidence of cancer has not been thoroughly examined in African Americans. We conducted a nested case-control study including 1801 cancer cases and 3337 controls among African Americans from the Southern Community Cohort Study (SCCS) to examine the association between coffee drinking, as assessed by a semi-quantitative food frequency questionnaire, and the risk of four common cancers (lung, prostate, breast, colorectal). We used logistic regression adjusted for age, sex and cancer-specific risk factors. Overall, only ≤ 9.5% of African American cases and controls from the SCCS drank regular or decaffeinated coffee ≥ 2 times/day. After adjustment for major cancer-specific risk factors, coffee consumption was not statistically significantly associated with the risk of lung, breast, colorectal, or prostate cancers (OR range 0.78-1.10; P ≥ 0.27 for ≥ 2 versus < 1 times/day) or overall cancer risk (OR 0.93; 95% CI 0.75-1.16; P = 0.52 for ≥ 2 versus < 1 times/day). Coffee consumption was not associated with the risk of cancer among African Americans in our study.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • African Americans / statistics & numerical data*
  • Age Factors
  • Case-Control Studies
  • Coffee* / adverse effects
  • Cohort Studies
  • Feeding Behavior / physiology*
  • Female
  • Humans
  • Male
  • Negative Results*
  • Neoplasms / epidemiology*
  • Neoplasms / etiology*
  • Neoplasms / prevention & control
  • Prevalence
  • Risk
  • Risk Factors
  • Sex Factors
  • Surveys and Questionnaires
  • United States

Substances

  • Coffee