A rare case of nitrofurantoin-induced acute lung injury

Rehan Karmali; Kyle Stawitzky; Isrin Srisethnil; Kaitlyn Simpson

doi:10.1002/ccr3.3314

A rare case of nitrofurantoin-induced acute lung injury

Clin Case Rep. 2020 Sep 16;8(10):2029-2033. doi: 10.1002/ccr3.3314. eCollection 2020 Oct.

Authors

Rehan Karmali¹, Kyle Stawitzky¹, Isrin Srisethnil¹, Kaitlyn Simpson²

Affiliations

¹ Touro College of Osteopathic Medicine Middletown New York USA.
² Department of Family Medicine Garnet Health Medical Center Middletown New York USA.

Abstract

Nitrofurantoin is a common treatment for urinary tract infections. Acute lung injury resulting from nitrofurantoin is a rare, life-threatening complication with women being at greater risk. Symptoms include respiratory distress with fevers, rash, eosinophilia, and new-onset atrial fibrillation. Treatment includes discontinuing the drug and possibly glucocorticoids for persistent oxygen demand.

Keywords: acute lung injury; drug‐induced pulmonary toxicity; nitrofurantoin.

Publication types

Case Reports