Serologic Responses in Healthy Adult with SARS-CoV-2 Reinfection, Hong Kong, August 2020

Emerg Infect Dis. 2020 Dec;26(12):3076-3078. doi: 10.3201/eid2612.203833. Epub 2020 Oct 22.


In March 2020, mild signs and symptoms of coronavirus disease developed in a healthy 33-year-old man in Hong Kong. His first infection did not produce virus neutralizing antibodies. In August, he had asymptomatic reinfection, suggesting that persons without a robust neutralizing antibody response might be at risk for reinfection.

Keywords: 2019 novel coronavirus disease; COVID-19; Hong Kong; SARS-CoV-2; antibodies; coronavirus disease; coronaviruses; immune response; reinfection; respiratory infections; serology; severe acute respiratory syndrome coronavirus 2; viruses; zoonoses.

Publication types

  • Case Reports
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antibody Formation / immunology
  • COVID-19 / immunology*
  • Hong Kong
  • Humans
  • Male
  • Pandemics
  • Reinfection / diagnosis*
  • SARS-CoV-2
  • Young Adult