[Clinico-pathological evaluation of keloids treated with intralesional injections of corticoid]

Med Cutan Ibero Lat Am. 1987;15(2):151-6.
[Article in Portuguese]

Abstract

37 keloid patients were treated with triamcinolone intralesionally every 15 days, in all 6 inoculations. Histologically after the treatment we observed alterations in dermal vascularization, in morphology, in color characteristics and in the arrangement of the collagen bundles. The disappearance of mucin and the presence of palisade granulomas was observed in some cases probably because of the corticoid deposited. There was regression of pruritus and pain in all the patients. We believe that the intralesionally infiltration of corticoid is even today one of the best methods of treatment, and it may also be effected together with other technics.

Publication types

  • English Abstract

MeSH terms

  • Adolescent
  • Adult
  • Child
  • Child, Preschool
  • Collagen / metabolism
  • Female
  • Humans
  • Injections
  • Keloid / drug therapy*
  • Keloid / metabolism
  • Keloid / pathology
  • Male
  • Middle Aged
  • Triamcinolone Acetonide / administration & dosage*
  • Triamcinolone Acetonide / pharmacology
  • Triamcinolone Acetonide / therapeutic use

Substances

  • Collagen
  • Triamcinolone Acetonide