Sociodemographic features and mortality of individuals on haemodialysis treatment who test positive for SARS-CoV-2: A UK Renal Registry data analysis

PLoS One. 2020 Oct 23;15(10):e0241263. doi: 10.1371/journal.pone.0241263. eCollection 2020.

Abstract

Kidney disease is a recognised risk factor for poor COVID-19 outcomes. Up to 30 June 2020, the UK Renal Registry (UKRR) collected data for 2,385 in-centre haemodialysis (ICHD) patients with COVID-19 in England and Wales. Overall unadjusted survival at 1 week after date of positive COVID-19 test was 87.5% (95% CI 86.1-88.8%); mortality increased with age, treatment vintage and there was borderline evidence of Asian ethnicity (HR 1.16, 95% CI 0.94-1.44) being associated with higher mortality. Compared to the general population, the relative risk of mortality for ICHD patients with COVID-19 was 45.4 and highest in younger adults. This retrospective cohort study based on UKRR data supports efforts to protect this vulnerable patient group.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Asian Continental Ancestry Group
  • Betacoronavirus*
  • COVID-19
  • Coronavirus Infections / epidemiology*
  • Coronavirus Infections / ethnology
  • Coronavirus Infections / mortality*
  • Coronavirus Infections / virology
  • Data Analysis
  • England / epidemiology
  • Female
  • Humans
  • Kidney Failure, Chronic / therapy
  • Male
  • Middle Aged
  • Pandemics
  • Pneumonia, Viral / epidemiology*
  • Pneumonia, Viral / ethnology
  • Pneumonia, Viral / mortality*
  • Pneumonia, Viral / virology
  • Registries*
  • Renal Dialysis*
  • Retrospective Studies
  • Risk Factors
  • SARS-CoV-2
  • Wales / epidemiology
  • Young Adult

Grant support

The author(s) received no specific funding for this work.