Association of antimicrobial photodynamic therapy and photobiomodulation for herpes simplex labialis resolution: Case series

Andrea Dias Neves Lago; Adylla Bianca Coelho Fortes; Guilherme Silva Furtado; Carlos Felipe Sousa Menezes; Letícia Machado Gonçalves

doi:10.1016/j.pdpdt.2020.102070

Association of antimicrobial photodynamic therapy and photobiomodulation for herpes simplex labialis resolution: Case series

Photodiagnosis Photodyn Ther. 2020 Dec:32:102070. doi: 10.1016/j.pdpdt.2020.102070. Epub 2020 Oct 21.

Authors

Andrea Dias Neves Lago¹, Adylla Bianca Coelho Fortes², Guilherme Silva Furtado³, Carlos Felipe Sousa Menezes⁴, Letícia Machado Gonçalves⁵

Affiliations

¹ Department of Dentistry I, Federal University of Maranhão - UFMA, Av. dos Portugueses, 1966, Bacanga, Zip Code: 65080-805, São Luís, MA, Brazil. Electronic address: andrea.lago@ufma.br.
² Department of Dentistry I, Federal University of Maranhão - UFMA, Av. dos Portugueses, 1966, Bacanga, Zip Code: 65080-805, São Luís, MA, Brazil. Electronic address: bia.adila@hotmail.com.
³ Department of Dentistry I, Federal University of Maranhão - UFMA, Av. dos Portugueses, 1966, Bacanga, Zip Code: 65080-805, São Luís, MA, Brazil. Electronic address: gfurtado.ufma@gmail.com.
⁴ Program in Dentistry, Federal University of Maranhão - UFMA, Av. dos Portugueses, 1966, Bacanga, São Luís, Maranhão, 65080-805 Brazil. Electronic address: carllos_fellipe@hotmail.com.
⁵ Department of Dentistry I, Federal University of Maranhão - UFMA, Av. dos Portugueses, 1966, Bacanga, Zip Code: 65080-805, São Luís, MA, Brazil. Electronic address: leticia.goncalves@ufma.br.

PMID: 33099039
DOI: 10.1016/j.pdpdt.2020.102070

Abstract

Antimicrobial Photodynamic Therapy (aPDT) with photobiomodulation therapy (PBT) can be used in herpes simplex and may have a role in improving modulation of inflammatory process, pain relief and acceleration of tissue repair. This article reports through a case series, a proposal for an efficient resolution in clinical manifestations of herpes simplex labialis using aPDT associated with PBT.

Keywords: Diode laser; Herpes simplex; Methylene Blue; Photodynamic therapy.

MeSH terms

Anti-Infective Agents* / therapeutic use
Herpes Labialis* / drug therapy
Herpes Simplex* / drug therapy
Humans
Methylene Blue / therapeutic use
Photochemotherapy* / methods
Photosensitizing Agents / therapeutic use

Substances

Anti-Infective Agents
Photosensitizing Agents
Methylene Blue