Screening for Prostate Cancer

Med Clin North Am. 2020 Nov;104(6):1051-1062. doi: 10.1016/j.mcna.2020.08.007. Epub 2020 Sep 16.

Abstract

This article gives an overview of the current state of the evidence for prostate cancer early detection with prostate-specific antigen (PSA) and summarizes current recommendations from guideline groups. The article reviews the global public health burden and risk factors for prostate cancer with clinical implications as screening tools. Screening studies, novel biomarkers, and MRI are discussed. The article outlines 7 key practice points for primary care physicians and provides a simple schema for facilitating shared decision-making conversations.

Keywords: Biomarkers; Magnetic resonance imaging; Prostate cancer; Prostate-specific antigen; Screening.

Publication types

  • Review

MeSH terms

  • Humans
  • Male
  • Primary Health Care
  • Prostate-Specific Antigen / blood
  • Prostatic Neoplasms / blood
  • Prostatic Neoplasms / diagnostic imaging
  • Prostatic Neoplasms / pathology
  • Prostatic Neoplasms / prevention & control*
  • United States

Substances

  • Prostate-Specific Antigen