Beneficial Effects of Near-Infrared Light Photobiomodulation in Linear Morphea: A Case Report

Photobiomodul Photomed Laser Surg. 2020 Nov;38(11):679-682. doi: 10.1089/photob.2020.4840. Epub 2020 Oct 27.


Background: Linear morphea is a variant of scleroderma limited to the skin and underlying tissues secondary to an autoimmune inflammation leading to excess collagen deposition and fibrosis. Apart from topical or oral medications, successful light-based treatments have been reported using phototherapy including Psoralen plus ultraviolet A, photodynamic therapy, carbon dioxide laser, pulsed dye laser, and visible/infrared light. Methods: We report a patient with biopsy-proven infraorbital linear morphea responding to 940 nm near-infrared light photobiomodulation treatments. Results: The patient had excellent cosmesis without textural changes or hypopigmentation despite her darker skin complexion (Fitzpatrick phototype III) after tri-weekly treatments for 8 months. Conclusions: Linear morphea, therefore, may be potentially amenable to home use light-based therapy by using nonthermal nonablative 940 nm photons. To our knowledge, this home-based treatment approach has not been previously reported.

Keywords: autoimmune; infrared; morphea; photobiomodulation; scleroderma; skin.

Publication types

  • Case Reports

MeSH terms

  • Female
  • Humans
  • Infrared Rays
  • Lasers, Gas*
  • Phototherapy
  • Scleroderma, Localized* / therapy
  • Skin