A Rare Axonal Variant of Guillain-Barré Syndrome as a Neurological Complication of COVID-19 Infection

Arch Iran Med. 2020 Oct 1;23(10):718-721. doi: 10.34172/aim.2020.93.


Guillain-Barré syndrome (GBS) is a neurological disorder accompanied by several neurological signs and symptoms including progressive weakness and diminished or decreased reflexes. GBS was reported as one of the several neurological complications in MERS-CoV and SARS-CoV outbreaks. Several studies have reported GBS as a neurological complication in recent COVID-19 outbreak. We report on the case of a 55-years -old female who was hospitalized with dyspnea, dry cough, and myalgia. She developed Acute Motor & Sensory Axonal Neuropathy (AMSAN), a rare variant of GBS signs and symptoms including decreased muscle strength and pinprick sensation in both lower extremities during her hospitalization.

Keywords: Axonal neuropathy; COVID-19; Dyspnea; Guillain-Barre syndrome; Muscle strength.

Publication types

  • Case Reports

MeSH terms

  • Betacoronavirus*
  • COVID-19
  • Coronavirus Infections / complications*
  • Coronavirus Infections / diagnosis
  • Coronavirus Infections / therapy
  • Female
  • Guillain-Barre Syndrome / diagnosis*
  • Guillain-Barre Syndrome / therapy
  • Guillain-Barre Syndrome / virology*
  • Humans
  • Middle Aged
  • Pandemics
  • Pneumonia, Viral / complications*
  • Pneumonia, Viral / diagnosis
  • Pneumonia, Viral / therapy
  • SARS-CoV-2