Metal-Free Intramolecular Aminophosphination of Allenes

J Org Chem. 2020 Dec 4;85(23):15686-15692. doi: 10.1021/acs.joc.0c02169. Epub 2020 Oct 29.


A metal-free intramolecular aminophosphination of sulfonamidoallenes with diarylphosphine oxides and Tf2O was developed. This method offers a general and practical procedure to construct valuable alkenylphosphine-substituted N-heterocycles via the bifunctionalization reaction of allenes in good yields under mild conditions.