Association of SARS-CoV-2 Genomic Load with Outcomes in Patients with COVID-19

doi:10.1513/AnnalsATS.202008-931RL

. 2021 May;18(5):900-903.

doi: 10.1513/AnnalsATS.202008-931RL.

Association of SARS-CoV-2 Genomic Load with Outcomes in Patients with COVID-19

Ioannis M Zacharioudakis¹, Prithiv J Prasad¹, Fainareti N Zervou¹, Atreyee Basu¹, Kenneth Inglima¹, Scott A Weisenberg¹, Maria E Aguero-Rosenfeld¹

Affiliations

PMID: 33119425
PMCID: PMC8086542
DOI: 10.1513/AnnalsATS.202008-931RL

Association of SARS-CoV-2 Genomic Load with Outcomes in Patients with COVID-19

Ioannis M Zacharioudakis et al. Ann Am Thorac Soc. 2021 May.

. 2021 May;18(5):900-903.

doi: 10.1513/AnnalsATS.202008-931RL.

Authors

Ioannis M Zacharioudakis¹, Prithiv J Prasad¹, Fainareti N Zervou¹, Atreyee Basu¹, Kenneth Inglima¹, Scott A Weisenberg¹, Maria E Aguero-Rosenfeld¹

Affiliation

¹ New York University Grossman School of Medicine New York, New York.

PMID: 33119425
PMCID: PMC8086542
DOI: 10.1513/AnnalsATS.202008-931RL

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Figures

**Figure 1.**
(A) Prediction of outcomes based on genomic load category. (B) Prediction of outcomes based on cycles threshold. (C) Prediction of outcomes based on genomic load and pneumonia severity index. CI = confidence interval.

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References

1. Centers for Systems Science and Engineering Coronavirus COVID-19 global cases Baltimore, MD: Johns Hopkins University; 2019[accessed 2020 Sep 20]. Available from: https://gisanddata.maps.arcgis.com/apps/opsdashboard/index.html
1. Phua J, Weng L, Ling L, Egi M, Lim CM, Divatia JV, et al. Asian Critical Care Clinical Trials Group Intensive care management of coronavirus disease 2019 (COVID-19): challenges and recommendations Lancet Respir Med 20208506–517.[Published erratum appears in Lancet Respir Med 8:e42.] - PMC - PubMed
1. Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020;395:1054–1062. - PMC - PubMed
1. Zhang J, Wang X, Jia X, Li J, Hu K, Chen G, et al. Risk factors for disease severity, unimprovement, and mortality in COVID-19 patients in Wuhan, China. Clin Microbiol Infect. 2020;26:767–772. - PMC - PubMed
1. Ji D, Zhang D, Xu J, Chen Z, Yang T, Zhao P, et al. Prediction for progression risk in patients with COVID-19 pneumonia: the CALL score. Clin Infect Dis. 2020;71:1393–1399. - PMC - PubMed

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[1] Centers for Systems Science and Engineering Coronavirus COVID-19 global cases Baltimore, MD: Johns Hopkins University; 2019[accessed 2020 Sep 20]. Available from: https://gisanddata.maps.arcgis.com/apps/opsdashboard/index.html

[2] Centers for Systems Science and Engineering Coronavirus COVID-19 global cases Baltimore, MD: Johns Hopkins University; 2019[accessed 2020 Sep 20]. Available from: https://gisanddata.maps.arcgis.com/apps/opsdashboard/index.html

[3] Phua J, Weng L, Ling L, Egi M, Lim CM, Divatia JV, et al. Asian Critical Care Clinical Trials Group Intensive care management of coronavirus disease 2019 (COVID-19): challenges and recommendations Lancet Respir Med 20208506–517.[Published erratum appears in Lancet Respir Med 8:e42.] - PMC - PubMed

[4] Phua J, Weng L, Ling L, Egi M, Lim CM, Divatia JV, et al. Asian Critical Care Clinical Trials Group Intensive care management of coronavirus disease 2019 (COVID-19): challenges and recommendations Lancet Respir Med 20208506–517.[Published erratum appears in Lancet Respir Med 8:e42.] - PMC - PubMed

[5] Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020;395:1054–1062. - PMC - PubMed

[6] Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020;395:1054–1062. - PMC - PubMed

[7] Zhang J, Wang X, Jia X, Li J, Hu K, Chen G, et al. Risk factors for disease severity, unimprovement, and mortality in COVID-19 patients in Wuhan, China. Clin Microbiol Infect. 2020;26:767–772. - PMC - PubMed

[8] Zhang J, Wang X, Jia X, Li J, Hu K, Chen G, et al. Risk factors for disease severity, unimprovement, and mortality in COVID-19 patients in Wuhan, China. Clin Microbiol Infect. 2020;26:767–772. - PMC - PubMed

[9] Ji D, Zhang D, Xu J, Chen Z, Yang T, Zhao P, et al. Prediction for progression risk in patients with COVID-19 pneumonia: the CALL score. Clin Infect Dis. 2020;71:1393–1399. - PMC - PubMed

[10] Ji D, Zhang D, Xu J, Chen Z, Yang T, Zhao P, et al. Prediction for progression risk in patients with COVID-19 pneumonia: the CALL score. Clin Infect Dis. 2020;71:1393–1399. - PMC - PubMed

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Association of SARS-CoV-2 Genomic Load with Outcomes in Patients with COVID-19

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Association of SARS-CoV-2 Genomic Load with Outcomes in Patients with COVID-19

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