Fecal Microbiota Transplantation in Dogs

Vet Clin North Am Small Anim Pract. 2021 Jan;51(1):219-233. doi: 10.1016/j.cvsm.2020.09.012. Epub 2020 Oct 29.

Abstract

In people, fecal microbiota transplantation is recognized as the best treatment modality for recurrent Clostridioides difficile infection in people, and its value is currently investigated in the treatment of other diseases associated with an abnormal gut microbiome. In dogs, intestinal dysbiosis has been documented in many acute and chronic digestive diseases as well as in diseases of other organ systems. There are only few published studies evaluating the benefits of fecal microbiota transplantation (FMT) in canine gastrointestinal disorders. They provide evidence that FMT may be beneficial in the treatment of acute intestinal diseases and hope that the technique might also be useful for the management of chronic enteropathies.

Keywords: Acute enteritis; Chronic enteropathy; Dog; Fecal microbiota transplantation; Intestinal metabolome; Intestinal microbiome.

Publication types

  • Review

MeSH terms

  • Animals
  • Clostridium Infections / therapy
  • Clostridium Infections / veterinary*
  • Dog Diseases / therapy*
  • Dogs
  • Dysbiosis / therapy
  • Dysbiosis / veterinary*
  • Fecal Microbiota Transplantation / veterinary*
  • Gastrointestinal Microbiome