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Review
. 2020 Oct 16:6:e27.
doi: 10.15420/cfr.2020.17. eCollection 2020 Mar.

Effects of Exercise Training on Cardiac Function in Heart Failure with Preserved Ejection Fraction

Hidekatsu Fukuta  1
Affiliations
Review

Effects of Exercise Training on Cardiac Function in Heart Failure with Preserved Ejection Fraction

Hidekatsu Fukuta. Card Fail Rev. .

Abstract

Nearly half of patients with heart failure in the community have heart failure with preserved ejection fraction (HFpEF). Patients with HFpEF are often elderly and their primary chronic symptom is severe exercise intolerance. Left ventricular diastolic dysfunction is associated with the pathophysiology of HFpEF and is an important contributor to exercise intolerance in HFpEF patients. The effects of exercise training on left ventricular diastolic function in HFpEF patients have been examined in several randomised clinical trials. Meta-analysis of the trials indicates that exercise training can provide clinically relevant improvements in exercise capacity without significant change in left ventricular structure or function in HFpEF patients. Further studies are necessary to elucidate the exact mechanisms of exercise intolerance in HFpEF patients and to develop recommendations regarding the most effective type, intensity, frequency, and duration of training in this group.

Keywords: Exercise; diastolic function; exercise capacity; functional electrical stimulation; inspiratory muscle training.

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Conflict of interest statement

Disclosure: The author has no conflicts of interest to declare.

Figures

Figure 1:
Figure 1:. Mechanisms of Improved Exercise Capacity With Exercise Training in HFpEF Patients
See this image and copyright information in PMC

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