Targeted tumor coating with antigenic, CTL-recognizable peptides via Annexin A5 chimeric constructs following chemotherapy redirects adaptive CD8+ T cell immunity for tumor clearance

Cell Mol Immunol. 2021 Jun;18(6):1578-1580. doi: 10.1038/s41423-020-00563-x. Epub 2020 Nov 2.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Annexin A5 / chemistry*
  • Antigens, Neoplasm / immunology*
  • Antineoplastic Agents / pharmacology
  • Antineoplastic Agents / therapeutic use*
  • Mice
  • Mice, Inbred C57BL
  • Neoplasms / drug therapy*
  • Neoplasms / immunology*
  • Neoplasms / pathology
  • Peptides / chemistry*
  • Recombinant Proteins / chemistry*
  • T-Lymphocytes, Cytotoxic / drug effects
  • T-Lymphocytes, Cytotoxic / immunology*
  • Tumor Microenvironment / drug effects

Substances

  • Annexin A5
  • Antigens, Neoplasm
  • Antineoplastic Agents
  • Peptides
  • Recombinant Proteins