Insomnia symptoms during pregnancy: A meta-analysis

J Sleep Res. 2021 Feb;30(1):e13207. doi: 10.1111/jsr.13207. Epub 2020 Nov 2.


Reports of sleep disturbances are common during pregnancy, yet estimates of prevalence of insomnia symptoms during pregnancy vary widely. The goals of the current review were to summarize the existing data on prevalence of insomnia symptoms during pregnancy and to explore potential moderators, including trimester, gestational age, maternal age, symptoms of anxiety and symptoms of depression. A systematic search of PubMed, PsycInfo and Web of Science was conducted for articles published from inception up to June 2020. In total, 24 studies with a total of 15,564 participants were included in the analysis. The overall prevalence of insomnia symptoms during pregnancy was 38.2%. Trimester was a significant moderator, such that prevalence of insomnia symptoms was higher in the third trimester (39.7%) compared to first (25.3%) and second (27.2%) trimesters. No other variables significantly moderated the prevalence of insomnia symptoms. The results of the current meta-analysis suggest that the prevalence of insomnia symptoms is higher during pregnancy, particularly in the third trimester. Future research should examine the efficacy and safety of insomnia treatments with this population.

Keywords: antepartum; prenatal; prepartum.

Publication types

  • Meta-Analysis
  • Review

MeSH terms

  • Adult
  • Female
  • Humans
  • Pregnancy
  • Pregnancy Complications / epidemiology*
  • Sleep Initiation and Maintenance Disorders / physiopathology*