Primary age-related tauopathy (PART) in the general autopsy setting: Not just a disease of the elderly

Brain Pathol. 2021 Mar;31(2):381-384. doi: 10.1111/bpa.12919. Epub 2021 Jan 5.

Abstract

Primary age-related tauopathy (PART) is generally considered a diagnosis of the elderly. In this letter, the authors present data showing that the pathologic changes of PART can occur in the general autopsy population significantly earlier than largely reported in the recent literature, particularly in woman.

Keywords: Alzheimer; PART; Tau; dementia; neurodegenerative.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Autopsy
  • Female
  • Humans
  • Male
  • Middle Aged
  • Tauopathies / epidemiology*
  • Tauopathies / pathology*