Contemporary Understanding of Ebola and Zika Virus in Pregnancy

Clin Perinatol. 2020 Dec;47(4):835-846. doi: 10.1016/j.clp.2020.08.005. Epub 2020 Oct 16.

Abstract

Understanding the pathophysiology, management, and prevention of emerging infectious diseases among pregnant women is imperative to achieve a successful response from the medical community. Ebola and Zika viruses represent infections with profound public health implications. In particular, Ebola virus is associated with high case fatality and pregnancy and neonatal loss rates, while Zika virus has been associated with multiple congenital anomalies; these features present critical clinical dilemmas for management of pregnant and reproductive aged women. The objective of this article is to summarize key background information and best practices for management of Ebola and Zika virus in pregnancy.

Keywords: Ebola virus; Emerging infectious diseases; Zika virus.

Publication types

  • Review

MeSH terms

  • Delivery, Obstetric
  • Female
  • Hemorrhagic Fever, Ebola / epidemiology
  • Hemorrhagic Fever, Ebola / prevention & control
  • Hemorrhagic Fever, Ebola / therapy*
  • Humans
  • Microcephaly
  • Mosquito Control
  • Mosquito Vectors
  • Personal Protective Equipment
  • Pregnancy
  • Pregnancy Complications, Infectious / epidemiology
  • Pregnancy Complications, Infectious / prevention & control
  • Pregnancy Complications, Infectious / therapy*
  • Zika Virus Infection / congenital
  • Zika Virus Infection / epidemiology
  • Zika Virus Infection / prevention & control
  • Zika Virus Infection / therapy*