Suboptimal moxifloxacin and levofloxacin drug exposure during treatment of patients with multidrug-resistant tuberculosis: results from a prospective study in China

Eur Respir J. 2021 Mar 11;57(3):2003463. doi: 10.1183/13993003.03463-2020. Print 2021 Mar.

Lina Davies Forsman^{1

2

3}, Katarina Niward^{4

5

3}, Johanna Kuhlin^{1

2}, Xubin Zheng⁶, Rongrong Zheng⁷, Ran Ke⁷, Chao Hong⁷, Jim Werngren⁸, Jakob Paues^{4

5}, Ulrika S H Simonsson⁹, Erik Eliasson¹⁰, Sven Hoffner¹¹, Biao Xu⁶, Jan-Willem Alffenaar^{12

13

14}, Thomas Schön^{4

15}, Yi Hu¹⁶, Judith Bruchfeld^{1

2}

¹ Division of Infectious Diseases, Dept of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.
² Dept of Infectious Diseases, Karolinska University Hospital Solna, Stockholm, Sweden.
³ Contributed equally.
⁴ Dept of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
⁵ Dept of Infectious Diseases, Linköping University Hospital, Linköping, Sweden.
⁶ Dept of Epidemiology, School of Public Health and Key Laboratory of Public Health Safety, Fudan University, Shanghai, China.
⁷ Dept of Tuberculosis and AIDS Prevention, Xiamen City Centre for Disease Control and Prevention, Fujian Province, China.
⁸ Dept of Microbiology, The Public Health Agency of Sweden, Stockholm, Sweden.
⁹ Dept of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden.
¹⁰ Dept of Laboratory Medicine, Division of Clinical Pharmacology, Karolinska University Hospital Huddinge, Stockholm, Sweden.
¹¹ Dept of Global Public Health, Karolinska Institutet, Stockholm, Sweden.
¹² Sydney Pharmacy School, Faculty of Medicine and Health, Sydney, Australia.
¹³ Marie Bashir Institute for Infectious Diseases and Biosecurity, Sydney, Australia.
¹⁴ University of Sydney, Westmead Hospital, Westmead, Australia.
¹⁵ Dept of Clinical Microbiology and Infectious Diseases, Kalmar County Hospital, Kalmar, Sweden.
¹⁶ Dept of Epidemiology, School of Public Health and Key Laboratory of Public Health Safety, Fudan University, Shanghai, China yhu@fudan.edu.cn.

No abstract available

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