Bronchiolitis obliterans and Nocardia asteroides infection of the lung

Chest. 1987 Dec;92(6):1107-8. doi: 10.1378/chest.92.6.1107.


This report describes a patient with right lower lung (RLL) pneumonia of a subacute nature. Sputum and bronchial washings both grew N asteroides. Open lung biopsy showed bronchiolitis obliterans. Both the clinical and radiologic picture dramatically improved during three weeks of treatment with trimethoprim and sulfamethoxazole (TMP - SMX), indicating the possibility that N asteroides infection contributed to bronchiolitis obliterans pneumonia in this patient.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Bronchiolitis Obliterans / diagnostic imaging
  • Bronchiolitis Obliterans / drug therapy
  • Bronchiolitis Obliterans / microbiology*
  • Bronchiolitis Obliterans / pathology
  • Humans
  • Male
  • Nocardia Infections / complications*
  • Nocardia Infections / drug therapy
  • Nocardia asteroides
  • Radiography
  • Sputum / microbiology
  • Sulfamethoxazole / therapeutic use
  • Trimethoprim / therapeutic use


  • Trimethoprim
  • Sulfamethoxazole