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. 2021 Apr;69(4):938-945.
doi: 10.1111/jgs.16915. Epub 2020 Nov 5.

Improvement in Activities of Daily Living during a Nursing Home Stay and One-Year Mortality among Older Adults with Sepsis

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Improvement in Activities of Daily Living during a Nursing Home Stay and One-Year Mortality among Older Adults with Sepsis

Brian Downer et al. J Am Geriatr Soc. 2021 Apr.

Abstract

Background/objective: To describe the recovery of activities of daily living (ADLs) during a skilled nursing facility (SNF) stay and the association with 1-year mortality after SNF discharge among Medicare beneficiaries treated in intensive care for sepsis.

Design: Retrospective cohort study.

Setting: Skilled nursing facilities in the United States.

Participants: Medicare fee-for-service beneficiaries admitted to an SNF within 3 days of discharge from a hospitalization that included an intensive care unit (ICU) stay for sepsis between January 1, 2013, and September 30, 2015 (N = 59,383).

Measurements: Data from the Minimum Data Set (MDS) were used to calculate a total score for seven ADLs. Improvement was determined by comparing the total ADL scores from the first and last MDS assessments of the SNF stay. Proportional hazard models were used to estimate the association between improvement in ADL function and 1-year mortality after SNF discharge.

Results: Approximately 58% of SNF residents had any improvement in ADL function. Residents who had improvement in ADL function had 0.72 (95% confidence interval (CI) = 0.69-0.74) lower risk for mortality following SNF discharge than residents who did not improve. Residents who improved 1-3 points (hazard ratio (HR) = 0.82, 95% CI = 0.79-0.84) and four or more points (HR = 0.57, 95% CI = 0.55-0.60) in ADL function had significantly lower mortality risk than residents who did not improve.

Conclusion: Older adults treated in an ICU with sepsis can improve in ADL function during an SNF stay. This improvement is associated with lower 1-year mortality risk after SNF discharge. These findings provide evidence that ADL recovery during an SNF stay is associated with better health outcomes for older adults who have survived an ICU stay for sepsis.

Keywords: skilled nursing facilities; sepsis; activities of daily living; mortality.

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Conflict of interest statement

Conflicts of Interest

No authors have conflicts of interest to report.

Figures

Figure 1:
Figure 1:
The selection of skilled nursing facility residents discharged from the hospital after an intensive care unit stay with sepsis.
Figure 2:
Figure 2:
The average marginal effects for the association between skilled nursing facility (SNF) resident characteristics at admission and any improvement in activities of daily living during a SNF stay.

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References

    1. Levy MM, Fink MP, Marshall JC, et al. 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Intensive Care Med. 2003;29: 530–538. - PubMed
    1. Paoli CJ, Reynolds MA, Sinha M, Gitlin M, Crouser E. Epidemiology and Costs of Sepsis in the United States-An Analysis Based on Timing of Diagnosis and Severity Level. Crit Care Med. 2018;46: 1889–1897. - PMC - PubMed
    1. Sjoding MW, Prescorr HC, Wunsch H, Iwashyna TJ, Coke CR. Longitudinal changes in intensive care unit admissions among elderly patients in the United States. Critical Care Medicine. 2016;44: 1353–1360. - PMC - PubMed
    1. Fan E, Cheek F, Chlan L, et al. An official American Thoracic Society Clinical Practice guideline: the diagnosis of intensive care unit-acquired weakness in adults. Am J Respir Crit Care Med. 2014;190: 1437–1446. - PubMed
    1. Elias MN, Munro CL, Liang Z, Calero K, Ji M. Sleep and Intensive Care Unit-Acquired Weakness in Critically Ill Older Adults. Dimens Crit Care Nurs. 2019;38: 20–28. - PubMed

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