Shiga Toxin-Producing Escherichia coli Transmission via Fecal Microbiota Transplant

Clin Infect Dis. 2021 Jun 1;72(11):e876-e880. doi: 10.1093/cid/ciaa1486.


Fecal microbiota transplantation (FMT) is recommended therapy for multiply recurrent Clostridioides difficile infection. We report adverse events in 7 patients who received FMT from a stool donor who was colonized with Shiga toxin-producing Escherichia coli (STEC). No patients died of FMT-transmitted STEC. Improved screening can likely avoid future transmission.

Keywords: Clostridioides difficile; FMT; STEC; Shiga toxin-producing E. coli; fecal microbiota transplantation.

MeSH terms

  • Clostridioides difficile*
  • Clostridium Infections*
  • Escherichia coli Infections*
  • Fecal Microbiota Transplantation
  • Feces
  • Humans
  • Microbiota*
  • Shiga-Toxigenic Escherichia coli*