Shiga Toxin-Producing Escherichia coli Transmission via Fecal Microbiota Transplant

Abstract

Fecal microbiota transplantation (FMT) is recommended therapy for multiply recurrent Clostridioides difficile infection. We report adverse events in 7 patients who received FMT from a stool donor who was colonized with Shiga toxin-producing Escherichia coli (STEC). No patients died of FMT-transmitted STEC. Improved screening can likely avoid future transmission.

Keywords: Clostridioides difficile; FMT; STEC; Shiga toxin-producing E. coli; fecal microbiota transplantation.