Shiga Toxin-Producing Escherichia coli Transmission via Fecal Microbiota Transplant

Clin Infect Dis. 2020 Sep 29;ciaa1486. doi: 10.1093/cid/ciaa1486. Online ahead of print.

Abstract

Fecal microbiota transplantation (FMT) is recommended therapy for multiply recurrent Clostridioides difficile infection. We report adverse events in 7 patients who received FMT from a stool donor who was colonized with Shiga toxin-producing Escherichia coli (STEC). No patients died of FMT-transmitted STEC. Improved screening can likely avoid future transmission.

Keywords: Clostridioides difficile; FMT; STEC; Shiga toxin-producing E. coli; fecal microbiota transplantation.