Resolution of confluent and reticulated papillomatosis after bariatric surgery

Clin Obes. 2021 Feb;11(1):e12427. doi: 10.1111/cob.12427. Epub 2020 Nov 8.

Abstract

Confluent and reticulated papillomatosis (CARP), a rare dermatologic disorder characterized by hyperpigmented papules that subsequently develop into plaques with reticulated margins, is frequently confused with acanthosis nigricans. The aetiology and pathogenesis of CARP is not yet fully understood, but it is often present in individuals with obesity and PCOS. This case report describes an African American adolescent female with obesity with a rash diagnosed as CARP after unsuccessful treatment with antifungals and corticosteroids. Her dermatosis proved recalcitrant to antibiotics and metformin but started to resolve immediately after bariatric surgery. This case report supports insulin resistance as a contributor to CARP's pathogenesis and as well as its association with obesity. Clinically significant weight reduction should be considered in the management of this challenging skin condition.

Keywords: confluent and reticulated papillomatosis and treatment; confluent and reticulated papillomatous and obesity; dermatosis and bariatric surgery.

Publication types

  • Case Reports

MeSH terms

  • Acanthosis Nigricans / drug therapy
  • Adolescent
  • Anti-Bacterial Agents / therapeutic use
  • Bariatric Surgery*
  • Female
  • Humans
  • Papilloma* / drug therapy
  • Papilloma* / surgery
  • Skin Neoplasms* / drug therapy

Substances

  • Anti-Bacterial Agents