Disseminated sporotrichosis with immune reconstitution inflammatory syndrome in an HIV patient: Case report and review of the literature

Vanice Rodrigues Poester; Lívia Silveira Munhoz; Rossana Patricia Basso; Beatriz Mendes Roca; Mariana Umpiérrez Vieira; Aryse Martins Melo; Gabriel Baracy Klafke; Karine Ortiz Sanchotene; Jussara Maria Silveira; David Stevens; Vanessa Brito de Souza Rabello; Rosely Maria Zancope-Oliveira; Melissa Orzechowski Xavier

doi:10.1016/j.riam.2020.09.001

Disseminated sporotrichosis with immune reconstitution inflammatory syndrome in an HIV patient: Case report and review of the literature

Rev Iberoam Micol. 2020 Jul-Oct;37(3-4):97-99. doi: 10.1016/j.riam.2020.09.001. Epub 2020 Nov 7.

Authors

Affiliations

¹ Programa de Pós Graduação em Ciências da Saúde, Faculdade de Medicina (FAMED), Universidade Federal do Rio Grande (FURG), RS, Brazil.
² Programa de Pós Graduação em Ciências da Saúde, Faculdade de Medicina (FAMED), Universidade Federal do Rio Grande (FURG), RS, Brazil; FAMED-FURG, Brazil.
³ FAMED-FURG, Brazil.
⁴ Programa de Pós-Graduação em Parasitologia, Universidade Federal de Pelotas (UFPel), Brazil.
⁵ California Institute for Medical Research, San Jose, California, and Div. of Infectious Diseases and Geographic Medicine, Stanford University Medical School, Stanford, CA, USA.
⁶ Laboratório de Micologia, Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, Brazil.
⁷ Programa de Pós Graduação em Ciências da Saúde, Faculdade de Medicina (FAMED), Universidade Federal do Rio Grande (FURG), RS, Brazil; FAMED-FURG, Brazil; Programa de Pós-Graduação em Parasitologia, Universidade Federal de Pelotas (UFPel), Brazil; California Institute for Medical Research, San Jose, California, and Div. of Infectious Diseases and Geographic Medicine, Stanford University Medical School, Stanford, CA, USA. Electronic address: melissaxavierfurg@gmail.com.

PMID: 33168342
DOI: 10.1016/j.riam.2020.09.001

Abstract

Background: Sporotrichosis has been occurring as outbreaks in Brazil, reaching epidemic levels in some regions. Zoonotic transmission is the main route to acquire Sporothrix.

Case report: We describe a case of disseminated sporotrichosis caused by Sporothrix brasiliensis in an HIV/AIDS patient, with the presentation of immune reconstitution inflammatory syndrome (IRIS).

Conclusions: This case reinforces that sporotrichosis should always be suspected in patients with IRIS from endemic regions, even in patients without the typical cutaneous lesions of this mycosis.

Keywords: AIDS; IRIS; SIRI; Sida; Sporothrix brasiliensis; Zoonosis.

Publication types

Case Reports
Review

MeSH terms

Acquired Immunodeficiency Syndrome*
Humans
Immune Reconstitution Inflammatory Syndrome*
Sporothrix*
Sporotrichosis*

Supplementary concepts

Sporothrix brasiliensis