A Novel Radiological Predictor for Postoperative Pancreatic Fistula After Stapled Distal Pancreatectomy

Am Surg. 2021 May;87(5):725-731. doi: 10.1177/0003134820952429. Epub 2020 Nov 10.

Abstract

Background: Distal pancreatectomy (DP) is the main surgical treatment of benign and malignant lesions located in pancreatic body and tail. Postoperative pancreatic fistula (POPF) following DP is still a considerable cause of morbidity. Identification of risk factors for POPF after DP might provide some preventive applications. We aimed to evaluate the factors affecting POPF after DP and to present a new and easy radiological predictive factor.

Materials and methods: Thirty-four patients underwent DP with stapler closure were included. Several risk factors for clinically relevant POPF (CR-POPF) were analyzed. Additionally, computed tomography findings of pancreatic thickness (PT), main pancreatic duct diameter (MPDD), and PT/MPDD ratio were evaluated for POPF.

Results: CR-POPF was observed in 10 patients (29.4%). Univariate and multivariate analyses showed that previous abdominal surgery and PT/MPDD ratio were predictive factors for CR-POPF after DP (P = 0.040, P = 0.034, respectively). The cutoff value for the PT/MPDD ratio was 8.

Conclusion: A PT/MPDD ratio greater than 8 (a wide pancreas with a narrow duct) is a significant predictive factor for CR-POPF following DP.

Keywords: pancreatic body and tail resection; pancreatic leak; risk.

Publication types

  • Evaluation Study

MeSH terms

  • Adult
  • Aged
  • Clinical Decision Rules*
  • Female
  • Humans
  • Logistic Models
  • Male
  • Middle Aged
  • Outcome Assessment, Health Care
  • Pancreas / diagnostic imaging*
  • Pancreas / surgery
  • Pancreatectomy* / methods
  • Pancreatic Fistula / diagnosis*
  • Pancreatic Fistula / etiology
  • Postoperative Complications / diagnosis*
  • Postoperative Complications / etiology
  • Retrospective Studies
  • Risk Assessment
  • Risk Factors
  • Surgical Stapling
  • Tomography, X-Ray Computed*