Botulinum Toxin Type-A for Lip Augmentation: "Lip Flip"

J Craniofac Surg. 2021 May 1;32(3):e273-e275. doi: 10.1097/SCS.0000000000007128.


Over the last 10 years there has been an explosion in the number of minimally invasive procedures that patients undertake with increasing uses of botulinum neurotoxin type A for off label indications. One area of expansion over the past several years is the "Lip Flip" which involves injection of botulinum neurotoxin type A along the vermillion border to improve lip contour, eversion and fullness. While techniques and results for "gummy smile" and perioral vertical rhytids have been previously reported, minimal literature exists on this new trend, including whether such increased interest truly exists. Therefore, the authors aim to explore whether there is a rising trend regarding "lip flip" and report on clinical results from patients treated in our practice.

MeSH terms

  • Botulinum Toxins, Type A*
  • Diagnosis, Oral
  • Humans
  • Lip
  • Smiling


  • Botulinum Toxins, Type A