Radiolabeled sucralfate has been utilized by several investigators to evaluate peptic ulcer, active inflammatory bowel disease, esophageal ulcer, and gastric cancer. A review of the available literature indicates that radiolabeled sucralfate has been used to evaluate peptic ulcer and active inflammatory bowel diseases with high sensitivity and specificity. Other possible uses of radiolabeled sucralfate which have been less thoroughly studied and for which data are inadequate to accurately determine sensitivity and specificity include the detection of gastric cancer and esophageal ulceration.