Gastritis: update on etiological features and histological practical approach

Pathologica. 2020 Sep;112(3):153-165. doi: 10.32074/1591-951X-163.


Gastric biopsies represent one of the most frequent specimens that the pathologist faces in routine activity. In the last decade or so, the landscape of gastric pathology has been changing with a significant and constant decline of H. pylori-related pathologies in Western countries coupled with the expansion of iatrogenic lesions due to the use of next-generation drugs in the oncological setting. This overview will focus on the description of the elementary lesions observed in gastric biopsies and on the most recent published recommendations, guidelines and expert opinions.

Keywords: H. pylori; endoscopy; gastritis; secondary prevention; staging.

Publication types

  • Review

MeSH terms

  • Biopsy
  • Endoscopy
  • Gastric Mucosa / pathology
  • Gastritis* / etiology
  • Gastritis* / pathology
  • Helicobacter pylori / pathogenicity
  • Humans
  • Neoplasm Grading
  • Precancerous Conditions / diagnosis
  • Precancerous Conditions / pathology
  • Risk Factors
  • Stomach Neoplasms / diagnosis
  • Stomach Neoplasms / etiology
  • Stomach Neoplasms / pathology